Genetic and anatomical basis of the barrier separating wakefulness and anesthetic-induced unresponsiveness.
A robust, bistable switch regulates the fluctuations between wakefulness and natural sleep as well as those between wakefulness and anesthetic-induced unresponsiveness.We previously provided experimental evidence for the existence of a behavioral barrier to transitions between these 6-0 igora vibrance states of arousal, which we call neural inertia